GDF11 Chemi-Luminescent ELISA Kit (Mouse) (OKCD05578)
Description of target: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role in the development of the nervous and other organ systems, and may regulate aging. Mice lacking a functional copy of this gene exhibit impaired anteroposterior patterning and other developmental defects.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: < 0.51pg/mL
