CD155:CD96 [Biotinylated] Inhibitor Screening Chemiluminescence Assay Kit

The CD155:CD96 [Biotinylated] Inhibitor Screening Chemiluminescence Assay Kit is an ELISA-based assay designed for screening and profiling molecules that block the binding between CD155 (cluster of differentiation 155) and CD96 (cluster of differentiation 96) . This kit comes in a convenient 96-well format, with enough recombinant human biotin-labeled CD96 (amino acids 22-503), CD155 (amino acids 27-343), streptavidin-labeled HRP, and assay buffer for 100 reactions.Figure 1: Illustration of the mechanism of CD155: CD96 [Biotinylated] Inhibitor Screening Chemiluminescence Assay Kit.A 96-well plate is coated with CD155 protein. After blocking, the plate is pre-incubated with an inhibitor or neutralizing antibody. After incubation with Biotin-CD96, the plate is washed and Streptavidin-HRP is added. The ELISA ECL substrate is added, and the resulting signal can be measured using a chemiluminescence microplate reader. The chemiluminescence signal is proportional to the binding of CD155 to CD96.Need us to run inhibitor screens or profile your compounds against CD155 binding to CD96? Check out ourImmunotherapy Biochemical Screening Services.